Clinical Presentation and Management of Patients Referred for a Transthoracic Echocardiography in the Canada’s Arctic Region

KEY TAKEAWAY: Examines diagnostic patterns and cardiac disease burden among remote Arctic populations receiving point-of-care and visiting echocardiographic services. Demonstrates that local outreach diagnostic services are critical for addressing unique regional health disparities.

Abstract

Background

Indigenous populations in Canada experience disproportionately high cardiovascular risk, yet contemporary data on echocardiographic findings in the Arctic remain limited. This study evaluated indications, echocardiographic findings, and subsequent management of patients undergoing transthoracic echocardiography in Eastern Nunavut.

Methods

We conducted a retrospective analysis of all consecutive transthoracic echocardiograms performed between January 2020 and December 2023 in Iqaluit and surrounding remote communities. Demographic data, echocardiographic results, and management decisions were collected and compared between Indigenous and non-Indigenous patients. Significant abnormalities were defined as moderate or severe valvular heart disease (VHD), prosthetic valve dysfunction, left ventricular ejection fraction (LVEF) < 50%, regional wall-motion abnormalities (RWMA), systolic pulmonary artery pressure ≥ 40 mm Hg, or congenital heart disease.

Results

Among 662 patients (mean age 55 ± 16 years; 47% women), 530 (80%) were Indigenous. Significant abnormalities were identified in 197 patients (30%). Moderate or severe VHD was present in 67 patients (10%), most commonly degenerative (31%), followed by functional (25%) and rheumatic (16%) etiologies. Reduced LVEF was seen in 16%, and RWMA was seen in 7%. Management included local follow-up (44%), transfer or hospital admission (16%), and tertiary-care referral (9%). Compared to non-Indigenous patients, Indigenous patients had higher unadjusted rates of significant abnormalities (33% vs 18%, P < 0.01), moderate or severe VHD (12% vs 5%, P = 0.04), and reduced LVEF or RWMA (21% vs 13%, P = 0.07).

Conclusions

Patients in Canada’s Arctic, particularly Indigenous communities, carry a substantial burden of cardiac disease, including elevated rates of VHD and ventricular dysfunction. Improved prevention and access to cardiovascular care are essential to reduce these disparities.

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Heart failure among 173,000 community-dwelling participants from 25 low-, middle-, and high-income countries in the PURE study

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Peer support for women with heart disease: program description and evaluation of Women@Heart